Localized Metagenomic Sequencing Center, Wuhan Jinyintan Hospital
In March 2020, there are about 11,000 patients with the symptoms of severe novel coronavirus pneumonia in hospitals in Wuhan City, as the designated hospital for treating novel coronavirus pneumonia , Wuhan jinyintan hospital has more than 500 patients who were in severe illness and critical illness. Severe and critical new coronary pneumonia is often accompanied by complicated infections such as bacteria and fungi, which is an important cause of death of patients. . Timely and accurate pathogen diagnosis is essential. At present, microbial culture is difficult to meet the needs of clinical treatments. NGS can quickly and accurately diagnose pathogens and provide real-time evidences for clinical treatments.
During the Lockdown of Wuhan city, the samples are not able to send out. MatriDx associated with Tongji Medical College of Huazhong university of Science & Technology, Alibaba Cloud and illumina to build the local microbial mNGS center in Wuhan jinyintan hospita in a short time. With the NGS technology, It helps more than 300 critically ill patients to get accurate diagnosis and treatments in time, reduces the mortality rate effectively.
Huashan Hospital of Fudan University – MatriDx Molecular diagnostic laboratory
Huashan Hospital of Fudan University -MatriDx Molecular Diagnostic Laboratory is a Clinical scientific research laboratory which jointly led by Institute of Antibiotics of Huashan Hospital of Fudan University(State Key Laboratory) and Hangzhou MatriDx Biotechnology Co Ltd.
The laboratory is equipped with the Matridx microbial mNGS localized technology platform which includes NGSmaster™ automated library preparation instrument, Intelligent data analysis system and illumina NextSeq™550Dx sequencer. It supports the localization of the mNGS in hospital, and the whole process of mNGS from sample to report can be completed within 13 hours. The laboratory will undertake the multi-center research projects on accurate diagnosis of infection, Accelerate the innovation and clinical application of mNGS technology by carrying out basic research and transformation.